Metabolomics in environmental toxicology: Applications and challenges

Metabolomics in toxicology: preclinical and clinical applications.

Metabolomics first burst into the toxicology arena approximately 10–12 years ago, experiencing rapid growth as a science in the intervening period (Fig. 1). Though metabolomics still trails the publication rates of its sister technologies, genomics and proteomics, it is closing the gap in terms of both the numbers of publications and the quality of those publications. One continuing source of c...

Environmental Toxicology in Addressing Public Health Challenges in East Asia

1Department of Environmental and Occupational Health, National Cheng Kung University, Tainan 704, Taiwan 2Department of Occupational and Environmental Medicine, National Cheng Kung University Hospital, Tainan 704, Taiwan 3Department of Environmental and Occupational Health, Universiti Putra Malaysia, 43400 Selangor, Malaysia 4Department of Occupational Medicine, Chi-Mei Medical Center, Tainan 7...

Metabolomics in toxicology and preclinical research.

Metabolomics, the comprehensive analysis of metabolites in a biological system, provides detailed information about the biochemical/physiological status of a biological system, and about the changes caused by chemicals. Metabolomics analysis is used in many fields, ranging from the analysis of the physiological status of genetically modified organisms in safety science to the evaluation of huma...

[Environmental toxicology].

Cardiovascular challenges in toxicology.

The diagnoses and subsequent treatment of poisoned patients manifesting cardiovascular compromise challenges the most experienced emergency physician. Numerous drugs and chemicals cause cardiac and vascular disorders. Despite widely varying indications for therapeutic use, many agents share a common cardiovascular pharmacologic effect if taken in overdose. Standard advanced cardiac life support...